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A novel quantitative approach for measuring the reservoir of latent HIV-1 proviruses
A stable latent reservoir for HIV-1 in resting CD4(+) T-cells precludes cure(1–3). Curative strategies targeting the reservoir are being tested(4,5) and require accurate, scalable reservoir assays. The reservoir was defined with quantitative viral outgrowth assays (QVOAs) for cells releasing infecti...
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| Gepubliceerd in: | Nature |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6447073/ https://ncbi.nlm.nih.gov/pubmed/30700913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-0898-8 |
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