Φορτώνει......
The thymoproteasome hardwires the TCR repertoire of CD8(+) T cells in the cortex independent of negative selection
The thymoproteasome expressed specifically in thymic cortical epithelium optimizes the generation of CD8(+) T cells; however, how the thymoproteasome contributes to CD8(+) T cell development is unclear. Here, we show that the thymoproteasome shapes the TCR repertoire directly in cortical thymocytes...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Exp Med |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Rockefeller University Press
2021
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7873839/ https://ncbi.nlm.nih.gov/pubmed/33555295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201904 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|