Selective nanoparticle-mediated targeting of renal tubular Toll-like receptor 9 attenuates ischemic acute kidney injury.

We developed an innovative therapy for ischemic acute kidney injury with discerning kidney-targeted delivery of a selective Toll-like receptor 9 (TLR9) antagonist in mice subjected to renal ischemia reperfusion injury. Our previous studies showed that mice deficient in renal proximal tubular TLR9 we...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Han, Sang Jun, Williams, Ryan M., D’Agati, Vivette, Jaimes, Edgar A., Heller, Daniel A., Lee, H. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872414/
https://ncbi.nlm.nih.gov/pubmed/32386967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2020.01.036
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