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Selective nanoparticle targeting of the renal tubules

Direct targeting to the kidneys is a promising strategy to improve drug therapeutic index for the treatment of kidney diseases. We sought to investigate the renal selectivity and safety of kidney-targeted “mesoscale” nanoparticle technology. We found that direct intravenous administration of these p...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Williams, Ryan M., Shah, Janki, Tian, Helen S., Chen, Xi, Geissmann, Frederic, Jaimes, Edgar A., Heller, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730475/
https://ncbi.nlm.nih.gov/pubmed/29133360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09843
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