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Kidney proximal tubular TLR9 exacerbates ischemic acute kidney injury
The role for kidney TLR9 in ischemic acute kidney injury (AKI) remains unclear. Here, we tested the hypothesis that renal proximal tubular TLR9 activation exacerbates ischemic AKI by promoting renal tubular epithelial apoptosis and inflammation. To test this hypothesis, we generated mice lacking TLR...
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| Izdano u: | J Immunol |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6057798/ https://ncbi.nlm.nih.gov/pubmed/29898963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800211 |
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