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Renal proximal tubular NEMO plays a critical role in ischemic acute kidney injury
We determined that renal proximal tubular (PT) NF-κB essential modulator (NEMO) plays a direct and critical role in ischemic acute kidney injury (AKI) using mice lacking renal PT NEMO and by targeted renal PT NEMO inhibition with mesoscale nanoparticle–encapsulated NEMO binding peptide (NBP MNP). We...
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| Publicat a: | JCI Insight |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566738/ https://ncbi.nlm.nih.gov/pubmed/32941183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139246 |
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