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Peptidyl arginine deiminase-4 exacerbates ischemic AKI by finding NEMO

Peptidyl arginine deiminase-4 (PAD4) catalyzes the conversion of peptidylarginine residues to peptidylcitrulline. We have previously shown that kidney ischemia-reperfusion (I/R) injury increases renal proximal tubular PAD4 expression and activity. Furthermore, kidney PAD4 plays a critical role in is...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Rabadi, May M., Han, Sang Jun, Kim, Mihwa, D’Agati, Vivette, Lee, H. Thomas
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620589/
https://ncbi.nlm.nih.gov/pubmed/30943066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00089.2019
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