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Norepinephrine released by intestinal Paneth cells exacerbates ischemic AKI

Small intestinal Paneth cells play a critical role in acute kidney injury (AKI) and remote organ dysfunction by synthesizing and releasing IL-17A. In addition, intestine-derived norepinephrine is a major mediator of hepatic injury and systemic inflammation in sepsis. We tested the hypothesis that sm...

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Détails bibliographiques
Publié dans:Am J Physiol Renal Physiol
Auteurs principaux: Han, Sang Jun, Kim, Mihwa, D’Agati, Vivette Denise, Lee, H. Thomas
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985817/
https://ncbi.nlm.nih.gov/pubmed/31813250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00471.2019
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