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Cholesterol access in cellular membranes controls Hedgehog signaling
The Hedgehog (Hh) signaling pathway coordinates cell–cell communication in development and regeneration. Defects in this pathway underlie diseases ranging from birth defects to cancer. Hh signals are transmitted across the plasma membrane by two proteins, Patched 1 (PTCH1) and Smoothened (SMO). PTCH...
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| Yayımlandı: | Nat Chem Biol |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7872078/ https://ncbi.nlm.nih.gov/pubmed/33199907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-00678-2 |
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