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Cholesterol access in cellular membranes controls Hedgehog signaling
The Hedgehog (Hh) signaling pathway coordinates cell–cell communication in development and regeneration. Defects in this pathway underlie diseases ranging from birth defects to cancer. Hh signals are transmitted across the plasma membrane by two proteins, Patched 1 (PTCH1) and Smoothened (SMO). PTCH...
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| Publicat a: | Nat Chem Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7872078/ https://ncbi.nlm.nih.gov/pubmed/33199907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-00678-2 |
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