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Cholesterol access in cellular membranes controls Hedgehog signaling
The Hedgehog (Hh) signaling pathway coordinates cell–cell communication in development and regeneration. Defects in this pathway underlie diseases ranging from birth defects to cancer. Hh signals are transmitted across the plasma membrane by two proteins, Patched 1 (PTCH1) and Smoothened (SMO). PTCH...
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| 出版年: | Nat Chem Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7872078/ https://ncbi.nlm.nih.gov/pubmed/33199907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-00678-2 |
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