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Coupling biocatalysis with high-energy flow reactions for the synthesis of carbamates and β-amino acid derivatives
A continuous flow process is presented that couples a Curtius rearrangement step with a biocatalytic impurity tagging strategy to produce a series of valuable Cbz-carbamate products. Immobilized CALB was exploited as a robust hydrolase to transform residual benzyl alcohol into easily separable benzy...
Gorde:
| Argitaratua izan da: | Beilstein J Org Chem |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Beilstein-Institut
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7871027/ https://ncbi.nlm.nih.gov/pubmed/33828617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.33 |
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