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Asymmetric synthesis of quaternary aryl amino acid derivatives via a three-component aryne coupling reaction
A method was developed for the synthesis of α-alkyl, α-aryl-bislactim ethers in good to excellent yields and high diastereoselectivities, consisting of a facile one-pot procedure in which the aryl group is introduced by means of a nucleophilic addition to benzyne and the alkyl group by alkylation of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Beilstein-Institut
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252860/ https://ncbi.nlm.nih.gov/pubmed/22238534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.185 |
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