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Asymmetric synthesis of quaternary aryl amino acid derivatives via a three-component aryne coupling reaction

A method was developed for the synthesis of α-alkyl, α-aryl-bislactim ethers in good to excellent yields and high diastereoselectivities, consisting of a facile one-pot procedure in which the aryl group is introduced by means of a nucleophilic addition to benzyne and the alkyl group by alkylation of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jones, Elizabeth P, Jones, Peter, White, Andrew J P, Barrett, Anthony G M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Beilstein-Institut 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252860/
https://ncbi.nlm.nih.gov/pubmed/22238534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.185
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