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Coupling biocatalysis with high-energy flow reactions for the synthesis of carbamates and β-amino acid derivatives
A continuous flow process is presented that couples a Curtius rearrangement step with a biocatalytic impurity tagging strategy to produce a series of valuable Cbz-carbamate products. Immobilized CALB was exploited as a robust hydrolase to transform residual benzyl alcohol into easily separable benzy...
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| izdano v: | Beilstein J Org Chem |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Beilstein-Institut
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7871027/ https://ncbi.nlm.nih.gov/pubmed/33828617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.33 |
| Oznake: |
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