Enzymatic synthesis of chiral amino‐alcohols by coupling transketolase and transaminase‐catalyzed reactions in a cascading continuous‐flow microreactor system

Rapid biocatalytic process development and intensification continues to be challenging with currently available methods. Chiral amino‐alcohols are of particular interest as they represent key industrial synthons for the production of complex molecules and optically pure pharmaceuticals. (2S,3R)‐2‐am...

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Vydáno v:Biotechnol Bioeng
Hlavní autoři: Gruber, Pia, Carvalho, Filipe, Marques, Marco P. C., O'Sullivan, Brian, Subrizi, Fabiana, Dobrijevic, Dragana, Ward, John, Hailes, Helen C., Fernandes, Pedro, Wohlgemuth, Roland, Baganz, Frank, Szita, Nicolas
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813273/
https://ncbi.nlm.nih.gov/pubmed/28986983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26470
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