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Enzymatic synthesis of chiral amino‐alcohols by coupling transketolase and transaminase‐catalyzed reactions in a cascading continuous‐flow microreactor system

Rapid biocatalytic process development and intensification continues to be challenging with currently available methods. Chiral amino‐alcohols are of particular interest as they represent key industrial synthons for the production of complex molecules and optically pure pharmaceuticals. (2S,3R)‐2‐am...

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Detalles Bibliográficos
Publicado en:Biotechnol Bioeng
Main Authors: Gruber, Pia, Carvalho, Filipe, Marques, Marco P. C., O'Sullivan, Brian, Subrizi, Fabiana, Dobrijevic, Dragana, Ward, John, Hailes, Helen C., Fernandes, Pedro, Wohlgemuth, Roland, Baganz, Frank, Szita, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813273/
https://ncbi.nlm.nih.gov/pubmed/28986983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26470
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