A Priori Activation of Apoptosis Pathways of Tumor (AAAPT) technology: Development of targeted apoptosis initiators for cancer treatment

Cancer cells develop tactics to circumvent the interventions by desensitizing themselves to interventions. Amongst many, the principle routes of desensitization include a) activation of survival pathways (e.g. NF-kB, PARP) and b) downregulation of cell death pathways (e.g. CD95/CD95L). As a result,...

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Publicado en:PLoS One
Main Authors: Pandurangi, Raghu S., Tomasetti, Marco, Verapazham, Sekar T., Paulmurugan, Ramasamy, Ma, Cynthia, Rajput, Sandeep, Anjanappa, Manjushree, Nakshatri, Harikrishna
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870153/
https://ncbi.nlm.nih.gov/pubmed/33556062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225869
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