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Dual TGFβ/BMP pathway inhibition enables expansion and characterization of multiple epithelial cell types of the normal and cancerous breast.

Functional modeling of normal breast epithelial hierarchy and stromal-epithelial cell interactions have been difficult due to inability to obtain sufficient stem-progenitor-mature epithelial and stromal cells. Recently reported epithelial reprogramming assay has partially overcome this limitation, b...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Prasad, Mayuri, Kumar, Brijesh, Bhat-Nakshatri, Poornima, Anjanappa, Manjushree, Sandusky, George, Miller, Kathy D., Storniolo, Anna Maria, Nakshatri, Harikrishna
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610652/
https://ncbi.nlm.nih.gov/pubmed/30992305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0165
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