A Priori Activation of Apoptosis Pathways of Tumor (AAAPT) technology: Development of targeted apoptosis initiators for cancer treatment

Cancer cells develop tactics to circumvent the interventions by desensitizing themselves to interventions. Amongst many, the principle routes of desensitization include a) activation of survival pathways (e.g. NF-kB, PARP) and b) downregulation of cell death pathways (e.g. CD95/CD95L). As a result,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pandurangi, Raghu S., Tomasetti, Marco, Verapazham, Sekar T., Paulmurugan, Ramasamy, Ma, Cynthia, Rajput, Sandeep, Anjanappa, Manjushree, Nakshatri, Harikrishna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870153/
https://ncbi.nlm.nih.gov/pubmed/33556062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225869
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