A Priori Activation of Apoptosis Pathways of Tumor (AAAPT) technology: Development of targeted apoptosis initiators for cancer treatment

Cancer cells develop tactics to circumvent the interventions by desensitizing themselves to interventions. Amongst many, the principle routes of desensitization include a) activation of survival pathways (e.g. NF-kB, PARP) and b) downregulation of cell death pathways (e.g. CD95/CD95L). As a result,...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Pandurangi, Raghu S., Tomasetti, Marco, Verapazham, Sekar T., Paulmurugan, Ramasamy, Ma, Cynthia, Rajput, Sandeep, Anjanappa, Manjushree, Nakshatri, Harikrishna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870153/
https://ncbi.nlm.nih.gov/pubmed/33556062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225869
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