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Molecular Simulations of Hydrophobic Gating of Pentameric Ligand Gated Ion Channels: Insights into Water and Ions
[Image: see text] Ion channels are proteins which form gated nanopores in biological membranes. Many channels exhibit hydrophobic gating, whereby functional closure of a pore occurs by local dewetting. The pentameric ligand gated ion channels (pLGICs) provide a biologically important example of hydr...
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| Udgivet i: | J Phys Chem B |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2021
|
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7869105/ https://ncbi.nlm.nih.gov/pubmed/33439645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c09285 |
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