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Water and hydrophobic gates in ion channels and nanopores

Ion channel proteins form nanopores in biological membranes which allow the passage of ions and water molecules. Hydrophobic constrictions in such pores can form gates, i.e. energetic barriers to water and ion permeation. Molecular dynamics simulations of water in ion channels may be used to assess...

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Detalhes bibliográficos
Publicado no:Faraday Discuss
Main Authors: Rao, Shanlin, Lynch, Charlotte I., Klesse, Gianni, Oakley, Georgia E., Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161260/
https://ncbi.nlm.nih.gov/pubmed/29969132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8fd00013a
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