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A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates

Ion channel proteins control ionic flux across biological membranes through conformational changes in their transmembrane pores. An exponentially increasing number of channel structures captured in different conformational states are now being determined; however, these newly resolved structures are...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rao, Shanlin, Klesse, Gianni, Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628796/
https://ncbi.nlm.nih.gov/pubmed/31235590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902702116
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