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JAK2 Inhibition by Fedratinib Reduces Osteoblast Differentiation and Mineralisation of Human Mesenchymal Stem Cells

Several signalling pathways, including the JAK/STAT signalling pathway, have been identified to regulate the differentiation of human bone marrow skeletal (mesenchymal) stem cells (hBMSCs) into bone-forming osteoblasts. Members of the JAK family mediate the intracellular signalling of various of cyt...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: AlMuraikhi, Nihal, Alaskar, Hanouf, Binhamdan, Sarah, Alotaibi, Amal, Kassem, Moustapha, Alfayez, Musaad
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866227/
https://ncbi.nlm.nih.gov/pubmed/33503825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030606
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