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JAK2 Inhibition by Fedratinib Reduces Osteoblast Differentiation and Mineralisation of Human Mesenchymal Stem Cells

Several signalling pathways, including the JAK/STAT signalling pathway, have been identified to regulate the differentiation of human bone marrow skeletal (mesenchymal) stem cells (hBMSCs) into bone-forming osteoblasts. Members of the JAK family mediate the intracellular signalling of various of cyt...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: AlMuraikhi, Nihal, Alaskar, Hanouf, Binhamdan, Sarah, Alotaibi, Amal, Kassem, Moustapha, Alfayez, Musaad
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866227/
https://ncbi.nlm.nih.gov/pubmed/33503825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030606
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