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Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells

Tankyrase is part of poly (ADP-ribose) polymerase superfamily required for numerous cellular and molecular processes. Tankyrase inhibition negatively regulates Wnt pathway. Thus, Tankyrase inhibitors have been extensively investigated for the treatment of clinical conditions associated with activate...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Almasoud, Nuha, Binhamdan, Sarah, Younis, Ghaydaa, Alaskar, Hanouf, Alotaibi, Amal, Manikandan, Muthurangan, Alfayez, Musaad, Kassem, Moustapha, AlMuraikhi, Nihal
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541626/
https://ncbi.nlm.nih.gov/pubmed/33028869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73439-9
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