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Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells

Tankyrase is part of poly (ADP-ribose) polymerase superfamily required for numerous cellular and molecular processes. Tankyrase inhibition negatively regulates Wnt pathway. Thus, Tankyrase inhibitors have been extensively investigated for the treatment of clinical conditions associated with activate...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Almasoud, Nuha, Binhamdan, Sarah, Younis, Ghaydaa, Alaskar, Hanouf, Alotaibi, Amal, Manikandan, Muthurangan, Alfayez, Musaad, Kassem, Moustapha, AlMuraikhi, Nihal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541626/
https://ncbi.nlm.nih.gov/pubmed/33028869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73439-9
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