Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells

BACKGROUND: Hedgehog (Hh) signaling is essential for osteoblast differentiation of mesenchymal progenitors during endochondral bone formation. However, the critical role of Hh signaling during adult bone remodeling remains to be elucidated. METHODS: A Smoothened (SMO) antagonist/Hedgehog inhibitor,...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Stem Cells Int
Autors principals: AlMuraikhi, Nihal, Almasoud, Nuha, Binhamdan, Sarah, Younis, Ghaydaa, Ali, Dalia, Manikandan, Muthurangan, Vishnubalaji, Radhakrishnan, Atteya, Muhammad, Siyal, Abdulaziz, Alfayez, Musaad, Aldahmash, Abdullah, Kassem, Moustapha, Alajez, Nehad M.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907053/
https://ncbi.nlm.nih.gov/pubmed/31871467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3435901
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars