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A Novel Role for the DNA Repair Enzyme 8-Oxoguanine DNA Glycosylase in Adipogenesis

Cells sustain constant oxidative stress from both exogenous and endogenous sources. When unmitigated by antioxidant defenses, reactive oxygen species damage cellular macromolecules, including DNA. Oxidative lesions in both nuclear and mitochondrial DNA are repaired via the base excision repair (BER)...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Komakula, Sai Santosh Babu, Blaze, Bhavya, Ye, Hong, Dobrzyn, Agnieszka, Sampath, Harini
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865743/
https://ncbi.nlm.nih.gov/pubmed/33503804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031152
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