8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle

Oxidative stress resulting from endogenous and exogenous sources causes damage to cellular components, including genomic and mitochondrial DNA. Oxidative DNA damage is primarily repaired via the base excision repair pathway that is initiated by DNA glycosylases. 8-oxoguanine DNA glycosylase (OGG1) r...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vartanian, Vladimir, Tumova, Jana, Dobrzyn, Pawel, Dobrzyn, Agnieszka, Nakabeppu, Yusaku, Lloyd, R. Stephen, Sampath, Harini
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519207/
https://ncbi.nlm.nih.gov/pubmed/28727777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181687
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