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The Interactions of DNA Repair, Telomere Homeostasis, and p53 Mutational Status in Solid Cancers: Risk, Prognosis, and Prediction

SIMPLE SUMMARY: p53 is a nuclear transcription factor with a pro-apoptotic function. Somatic mutations in this gene represent one of the most critical events in human carcinogenesis. The disruption of genomic integrity due to the accumulation of various kinds of DNA damage, deficient DNA repair capa...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Vodicka, Pavel, Andera, Ladislav, Opattova, Alena, Vodickova, Ludmila
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865496/
https://ncbi.nlm.nih.gov/pubmed/33513745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030479
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