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The Interactions of DNA Repair, Telomere Homeostasis, and p53 Mutational Status in Solid Cancers: Risk, Prognosis, and Prediction

SIMPLE SUMMARY: p53 is a nuclear transcription factor with a pro-apoptotic function. Somatic mutations in this gene represent one of the most critical events in human carcinogenesis. The disruption of genomic integrity due to the accumulation of various kinds of DNA damage, deficient DNA repair capa...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Vodicka, Pavel, Andera, Ladislav, Opattova, Alena, Vodickova, Ludmila
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865496/
https://ncbi.nlm.nih.gov/pubmed/33513745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030479
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