DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome

There is ample evidence for the essential involvement of DNA repair and DNA damage response in the onset of solid malignancies, including ovarian cancer. Indeed, high-penetrance germline mutations in DNA repair genes are important players in familial cancers: BRCA1, BRCA2 mutations or mismatch repai...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Tomasova, Kristyna, Cumova, Andrea, Seborova, Karolina, Horak, Josef, Koucka, Kamila, Vodickova, Ludmila, Vaclavikova, Radka, Vodicka, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408288/
https://ncbi.nlm.nih.gov/pubmed/32605254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071713
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