DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome

There is ample evidence for the essential involvement of DNA repair and DNA damage response in the onset of solid malignancies, including ovarian cancer. Indeed, high-penetrance germline mutations in DNA repair genes are important players in familial cancers: BRCA1, BRCA2 mutations or mismatch repai...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Tomasova, Kristyna, Cumova, Andrea, Seborova, Karolina, Horak, Josef, Koucka, Kamila, Vodickova, Ludmila, Vaclavikova, Radka, Vodicka, Pavel
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408288/
https://ncbi.nlm.nih.gov/pubmed/32605254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071713
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