Telomere status in chronic lymphocytic leukemia with TP53 disruption

In chronic lymphocytic leukemia (CLL), telomere dysfunction is associated with poor outcomes. TP53 is involved in cellular responses to dysfunctional telomeres, and its inactivation is the strongest adverse prognostic factor for CLL. Given the biological relationship between TP53 and telomeres, and...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Guièze, Romain, Pages, Mélanie, Véronèse, Lauren, Combes, Patricia, Lemal, Richard, Gay-bellile, Mathilde, Chauvet, Martine, Callanan, Mary, Kwiatkowski, Fabrice, Pereira, Bruno, Vago, Philippe, Bay, Jacques-Olivier, Tournilhac, Olivier, Tchirkov, Andreï
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302966/
https://ncbi.nlm.nih.gov/pubmed/27486974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10927
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