Adenovirus-vectored vaccine containing multidimensionally conserved parts of the HIV proteome is immunogenic in rhesus macaques

An effective vaccine that can protect against HIV infection does not exist. A major reason why a vaccine is not available is the high mutability of the virus, which enables it to evolve mutations that can evade human immune responses. This challenge is exacerbated by the ability of the virus to evol...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Murakowski, Dariusz K., Barton, John P., Peter, Lauren, Chandrashekar, Abishek, Bondzie, Esther, Gao, Ang, Barouch, Dan H., Chakraborty, Arup K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2021
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865178/
https://ncbi.nlm.nih.gov/pubmed/33514660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022496118
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