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Adenovirus-vectored vaccine containing multidimensionally conserved parts of the HIV proteome is immunogenic in rhesus macaques

An effective vaccine that can protect against HIV infection does not exist. A major reason why a vaccine is not available is the high mutability of the virus, which enables it to evolve mutations that can evade human immune responses. This challenge is exacerbated by the ability of the virus to evol...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Murakowski, Dariusz K., Barton, John P., Peter, Lauren, Chandrashekar, Abishek, Bondzie, Esther, Gao, Ang, Barouch, Dan H., Chakraborty, Arup K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865178/
https://ncbi.nlm.nih.gov/pubmed/33514660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022496118
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