Adenovirus-vectored vaccine containing multidimensionally conserved parts of the HIV proteome is immunogenic in rhesus macaques

An effective vaccine that can protect against HIV infection does not exist. A major reason why a vaccine is not available is the high mutability of the virus, which enables it to evolve mutations that can evade human immune responses. This challenge is exacerbated by the ability of the virus to evol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Murakowski, Dariusz K., Barton, John P., Peter, Lauren, Chandrashekar, Abishek, Bondzie, Esther, Gao, Ang, Barouch, Dan H., Chakraborty, Arup K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2021
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865178/
https://ncbi.nlm.nih.gov/pubmed/33514660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022496118
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