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Nonenzymatic polymerase-like template-directed synthesis of acyclic l-threoninol nucleic acid
Evolution of xeno nucleic acid (XNA) world essentially requires template-directed synthesis of XNA polymers. In this study, we demonstrate template-directed synthesis of an acyclic XNA, acyclic l-threoninol nucleic acid (l-aTNA), via chemical ligation mediated by N-cyanoimidazole. The ligation of an...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864931/ https://ncbi.nlm.nih.gov/pubmed/33547322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21128-0 |
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