VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs

The Wnt/β-catenin pathway is one of the major pathways that regulates embryonic development, adult homeostasis, and stem cell self-renewal. In this pathway, transcription factors T-cell factor and lymphoid enhancer factor (TCF/LEF) serve as a key switch to repress or activate Wnt target gene transcr...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Zhang, Haifeng, Rong, Xiaozhi, Wang, Caixia, Liu, Yunzhang, Lu, Ling, Li, Yun, Zhao, Chengtian, Zhou, Jianfeng
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2021
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864075/
https://ncbi.nlm.nih.gov/pubmed/32989053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015282
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