Glutathione peroxidase 4 inhibits Wnt/β-catenin signaling and regulates dorsal organizer formation in zebrafish embryos

The Wnt/β-catenin signaling pathway plays pivotal roles in axis formation during embryogenesis and in adult tissue homeostasis. Glutathione peroxidase 4 (GPX4) is a selenoenzyme and participates in the reduction of peroxides. Its synthesis depends on the availability of the element selenium. However...

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Rong, Xiaozhi, Zhou, Yumei, Liu, Yunzhang, Zhao, Beibei, Wang, Bo, Wang, Caixia, Gong, Xiaoxia, Tang, Peipei, Lu, Ling, Li, Yun, Zhao, Chengtian, Zhou, Jianfeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514413/
https://ncbi.nlm.nih.gov/pubmed/28302747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.144261
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