Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis

Neutrophils can function and survive in injured and infected tissues, where oxygen and metabolic substrates are limited. Using radioactive flux assays and LC-MS tracing with U-(13)C glucose, glutamine, and pyruvate, we observe that neutrophils require the generation of intracellular glycogen stores...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cell Metab
المؤلفون الرئيسيون: Sadiku, Pranvera, Willson, Joseph A., Ryan, Eilise M., Sammut, David, Coelho, Patricia, Watts, Emily R., Grecian, Robert, Young, Jason M., Bewley, Martin, Arienti, Simone, Mirchandani, Ananda S., Sanchez Garcia, Manuel A., Morrison, Tyler, Zhang, Ailing, Reyes, Leila, Griessler, Tobias, Jheeta, Privjyot, Paterson, Gordon G., Graham, Christopher J., Thomson, John P., Baillie, Kenneth, Thompson, A.A. Roger, Morgan, Jessie-May, Acosta-Sanchez, Abel, Dardé, Veronica M., Duran, Jordi, Guinovart, Joan J., Rodriguez-Blanco, Gio, Von Kriegsheim, Alex, Meehan, Richard R., Mazzone, Massimiliano, Dockrell, David H., Ghesquiere, Bart, Carmeliet, Peter, Whyte, Moira K.B., Walmsley, Sarah R.
التنسيق: Artigo
اللغة:Inglês
منشور في: Cell Press 2021
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863914/
https://ncbi.nlm.nih.gov/pubmed/33306983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.11.016
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