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A G(s)-RhoGEF interaction: An old G protein finds a new job

The heterotrimeric G proteins are known to have a variety of downstream effectors, but G(s) was long thought to be specifically coupled to adenylyl cyclases. A new study indicates that activated G(s) can also directly interact with a guanine nucleotide exchange factor for Rho family small GTPases, P...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Slepak, Vladlen Z., Pronin, Alexey
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863890/
https://ncbi.nlm.nih.gov/pubmed/33310745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.016606
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