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Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer

Macrophage migration inhibitory factor (MIF) is an upstream regulator of innate immunity, but its expression is increased in some cancers via stabilization with HSP90-associated chaperones. Here, we show that MIF stabilization is tumor-specific in an acute colitis-associated colorectal cancer (CRC)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Klemke, Luisa, De Oliveira, Tiago, Witt, Daria, Winkler, Nadine, Bohnenberger, Hanibal, Bucala, Richard, Conradi, Lena-Christin, Schulz-Heddergott, Ramona
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862487/
https://ncbi.nlm.nih.gov/pubmed/33542244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03426-z
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