טוען...
HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates
Constitutively stabilized HSP90 client proteins are crucial for cancer cell survival and proliferation. Thus, despite—or perhaps because of—their pleiotropic effects on variety of critical oncoproteins, HSP90 inhibitors represent a promising new class of anticancer drugs. We identified MIF as an ess...
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| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Landes Bioscience
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518525/ https://ncbi.nlm.nih.gov/pubmed/23243616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21173 |
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