UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance

UBE2O, an E2/E3 hybrid ubiquitin-protein ligase, has been implicated in the regulation of adipogenesis, erythroid differentiation, and tumor proliferation. However, its role in cancer radioresistance remains completely unknown. Here, we uncover that UBE2O interacts and targets Mxi1 for ubiquitinatio...

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Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Differ
Egile Nagusiak: Huang, Yumei, Yang, Xijie, Lu, Yanwei, Zhao, Ye, Meng, Rui, Zhang, Sheng, Dong, Xiaorong, Xu, Shuangbing, Wu, Gang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862231/
https://ncbi.nlm.nih.gov/pubmed/32901121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00616-8
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