A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination

Dysregulation of the Wnt/β-catenin signaling pathway is critically involved in gastric cancer (GC) progression. However, current Wnt pathway inhibitors being studied in preclinical or clinical settings for other cancers such as colorectal and pancreatic cancers are either too cytotoxic or insufficie...

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Detaylı Bibliyografya
Yayımlandı:Oncogene
Asıl Yazarlar: Yu, Zeyuan, Jiang, Xiangyan, Qin, Long, Deng, Haixiao, Wang, Jianli, Ren, Wen, Li, Hongbin, Zhao, Lei, Liu, Huanxiang, Yan, Hong, Shi, Wengui, Wang, Qi, Luo, Changjiang, Long, Bo, Zhou, Huinian, Sun, Hui, Jiao, Zuoyi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862066/
https://ncbi.nlm.nih.gov/pubmed/33323973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01572-w
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