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Separate signaling events control TCR downregulation and T cell activation in primary human T cells
INTRODUCTION: T‐cell antigen receptor (TCR) interaction with cognate peptide:MHC complexes trigger clustering of TCR:CD3 complexes and signal transduction. Triggered TCR:CD3 complexes are rapidly internalized and degraded in a process called ligand‐induced TCR downregulation. Classic studies in immo...
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| 發表在: | Immun Inflamm Dis |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7860602/ https://ncbi.nlm.nih.gov/pubmed/33350598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.383 |
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