Wird geladen...

Influence of the pK(a) Value of Cinnamic Acid and P-Hydroxycinnamic Acid on the Solubility of a Lurasidone Hydrochloride-Based Coamorphous System

[Image: see text] Coamorphization of a poorly water-soluble active pharmaceutical ingredient (API) has been proven to be effective in improving its solubility. Generally, API can form multiple coamorphous systems with different coformers. However, it remains unclear how the pK(a) value of different...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ACS Omega
Hauptverfasser: Hu, Yi, Guo, Yujie, Li, Bin, Xu, Renjie, Fang, Xiaoping, Cao, Yan, Liu, Zifan, Jiang, Cuiping, Lu, Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2021
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860058/
https://ncbi.nlm.nih.gov/pubmed/33553927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05510
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!