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Actin filament oxidation by MICAL1 suppresses protections from cofilin‐induced disassembly

Proteins of the ADF/cofilin family play a central role in the disassembly of actin filaments, and their activity must be tightly regulated in cells. Recently, the oxidation of actin filaments by the enzyme MICAL1 was found to amplify the severing action of cofilin through unclear mechanisms. Using s...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Wioland, Hugo, Frémont, Stéphane, Guichard, Bérengère, Echard, Arnaud, Jégou, Antoine, Romet‐Lemonne, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857426/
https://ncbi.nlm.nih.gov/pubmed/33393173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050965
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