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Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin

The ability of cells to generate forces through actin filament turnover was an early adaptation in evolution. While much is known about how actin filaments grow, mechanisms of their disassembly are incompletely understood. The best-characterized actin disassembly factors are the cofilin family prote...

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Vydáno v:Nat Commun
Hlavní autoři: Kotila, Tommi, Wioland, Hugo, Enkavi, Giray, Kogan, Konstantin, Vattulainen, Ilpo, Jégou, Antoine, Romet-Lemonne, Guillaume, Lappalainen, Pekka
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876575/
https://ncbi.nlm.nih.gov/pubmed/31757941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13213-2
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