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Methods for the discovery of small molecules to monitor and perturb the activity of the human proteasome
Regulating protein production and degradation is critical to maintaining cellular homeostasis. The proteasome is a key player in keeping proteins at the proper levels. However, proteasome activity can be altered in certain disease states, such as blood cancers and neurodegenerative diseases. Cancers...
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| Gepubliceerd in: | Future Med Chem |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Newlands Press Ltd
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7857359/ https://ncbi.nlm.nih.gov/pubmed/33275045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2020-0288 |
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